Yazar "Zolbanin, Hamed M." seçeneğine göre listele

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    An explanatory analytics framework for early detection of chronic risk factors in pandemics
    (Elsevier, 2022) Delen, Dursun; Delen, Dursun; Davazdahemami, Behrooz; Zolbanin, Hamed M.; Delen, Dursun; Yönetim Bilimleri Fakültesi, İşletme Bölümü; Yönetim Bilimleri Fakültesi, İşletme Bölümü
    Timely decision-making in national and global health emergencies such as pandemics is critically important from various aspects. Especially, early identification of risk factors of contagious viral diseases can lead to efficient management of limited healthcare resources and saving lives by prioritizing at-risk patients. In this study, we propose a hybrid artificial intelligence (AI) framework to identify major chronic risk factors of novel, contagious diseases as early as possible at the time of pandemics. The proposed framework combines evolutionary search algorithms with machine learning and the novel explanatory AI (XAI) methods to detect the most critical risk factors, use them to predict patients at high risk of mortality, and analyze the risk factors at the individual level for each high-risk patient. The proposed framework was validated using data from a repository of electronic health records of early COVID-19 patients in the US. A chronological analysis of the chronic risk factors identified using our proposed approach revealed that those factors could have been identified months before they were determined by clinical studies and/or announced by the United States health officials.
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    An explanatory machine learning framework for studying pandemics: The case of COVID-19 emergency department readmissions
    (Elsevier, 2022) Delen, Dursun; Delen, Dursun; Davazdahemami, Behrooz; Zolbanin, Hamed M.; Delen, Dursun; Yönetim Bilimleri Fakültesi, İşletme Bölümü; Yönetim Bilimleri Fakültesi, İşletme Bölümü
    One of the major challenges that confront medical experts during a pandemic is the time required to identify and validate the risk factors of the novel disease and to develop an effective treatment protocol. Traditionally, this process involves numerous clinical trials that may take up to several years, during which strict preventive measures must be in place to control the outbreak and reduce the deaths. Advanced data analytics techniques, however, can be leveraged to guide and speed up this process. In this study, we combine evolutionary search algorithms, deep learning, and advanced model interpretation methods to develop a holistic exploratory- predictive-explanatory machine learning framework that can assist clinical decision-makers in reacting to the challenges of a pandemic in a timely manner. The proposed framework is showcased in studying emergency department (ED) readmissions of COVID-19 patients using ED visits from a real-world electronic health records database. After an exploratory feature selection phase using genetic algorithm, we develop and train a deep artificial neural network to predict early (i.e., 7-day) readmissions (AUC = 0.883). Lastly, a SHAP model is formulated to estimate additive Shapley values (i.e., importance scores) of the features and to interpret the magnitude and direction of their effects. The findings are mostly in line with those reported by lengthy and expensive clinical trial studies.